The diagram below shows an mRNA molecule that encodes a protein with 202 amino acids. The start and stop codons are highlighted, and a portion of the nucleotide sequence in the early part of the molecule is shown in detail.
Based on the genetic code chart below, which of the following would be the result of this single base-pair substitution?
The diagram below shows an mRNA molecule that encodes a protein with 202 amino acids. The start and stop codons are highlighted, and a portion of the nucleotide sequence in the early part of the molecule is shown in detail. At position 35, a single base-pair substitution in the DNA has changed that would have been a uracil (U) in the mRNA to an adenine (A).
Based on the genetic code chart below, which of the following would be the result of this single base-pair substitution?
- A. a silent mutation (no change in the amino acid sequence of the protein)
- B. a frameshift mutation causing extensive change in the amino acid sequence of the protein
- C. a missense mutation causing a single amino acid change in the protein
- D. a frameshift mutation causing a single amino acid change in the protein
- E. a nonsense mutation resulting in early termination of translation
