Based on the genetic code chart below, which of the following would be the result of this single base-pair substitution?
Based on the genetic code chart below, which of the following would be the result of this single base-pair substitution?
The diagram below shows an mRNA molecule that encodes a protein with 202 amino acids. The start and stop codons are highlighted, and a portion of the nucleotide sequence in the early part of the molecule is shown in detail. At position 35, a single base-pair substitution in the DNA has changed that would have been a uracil (U) in the mRNA to an adenine (A).
Based on the genetic code chart below, which of the following would be the result of this single base-pair substitution?
- A. a silent mutation (no change in the amino acid sequence of the protein)
- B. a frameshift mutation causing extensive change in the amino acid sequence of the protein
- C. a missense mutation causing a single amino acid change in the protein
- D. a frameshift mutation causing a single amino acid change in the protein
- E. a nonsense mutation resulting in early termination of translation
