how many polypeptide chains does PFK-1 consist of?
1) how many polypeptide chains does PFK-1 consist of?
2) is it a homodimer, heterodimer, homotrimer, heterotrimer, homotetramer or heterotetramer? and how did you come to this conclusion?
3) What is involved in the folding and unfolding of a polypeptide chain? are hydrogen bonds formed and broken or covalent bonds and are they just formed/broken in the protein backbone or from one protein strand to another?
4) what kind of interaction is the interaction between one of the ADP sugar ring hydroxyl groups and a peptide backbone carbonyl? (pi-stacking, dipole-dipole, ion-ion, hydrophobic interaction and/or hydrogen bonding)
5) what interaction is found between the F6P phosphate group binding to the protein via interactions with 3 arginine sidechains? (pi-stacking, dipole-dipole, ion-ion, hydrophobic interaction and/or hydrogen bonding)
