Thyroid Diseases and Conditions; Researchers at National Cancer Institute Have Reported New Data on Thyroid Diseases (PBDE flame retardants, thyroid disease, and menopausal status in US women)

Thyroid Diseases and Conditions; Researchers at National Cancer Institute Have Reported New Data on Thyroid Diseases (PBDE flame retardants, thyroid disease, and menopausal status in US women) Publication info: Women’s Health Weekly ; Atlanta [Atlanta]23 June 2016: 4357.

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ABSTRACT

According to the news reporters, the research concluded: “Exposure to BDEs 47, 99, and 100 is associated with

thyroid disease in a national sample of U.S. women, with greater effects observed post-menopause, suggesting

that the disruption of thyroid signaling by PBDEs may be enhanced by the altered estrogen levels during

menopause.”

FULL TEXT

2016 JUN 23 (NewsRx) — By a News Reporter-Staff News Editor at Women’s Health Weekly — Fresh data on Thyroid

Diseases and Conditions are presented in a new report. According to news reporting from Research Triangle Park,

North Carolina, by NewsRx journalists, research stated, “Women have elevated rates of thyroid disease compared

to men. Environmental toxicants have been implicated as contributors to this dimorphism, including

polybrominated diphenyl ethers (PBDEs), flame retardant chemicals that disrupt thyroid hormone action.”

 

The news correspondents obtained a quote from the research from National Cancer Institute, “PBDEs have also

been implicated in the disruption of estrogenic activity, and estrogen levels regulate thyroid hormones. Post-

menopausal women may therefore be particularly vulnerable to PBDE induced thyroid effects, given low estrogen

reserves. The objective of this study was to test for an association between serum PBDE concentrations and

thyroid disease in women from the United States (U.S.), stratified by menopause status. Serum PBDE

concentrations (BDEs 47, 99, 100 and 153) from the National Health and Examination Survey (NHANES) and

reports on thyroid problems were available in the NHANES 2003-2004 cycle. Odds ratios (ORs) were calculated

using multivariate logistic regression models accounting for population-weighted survey techniques and

controlling for age, body mass index (BMI), education, smoking, alcohol consumption and thyroid medication.

Menopause status was obtained by self-reported absence of menstruation in the previous 12 months and declared

menopause. Women in the highest quartile of serum concentrations for BDEs 47, 99, and 100 had increased odds

of currently having thyroid disease (ORs: 1.5, 1.8, 1.5, respectively) compared to the reference group (1st and 2nd

quartiles combined); stronger associations were observed when the analysis was restricted to postmenopausal

women (ORs: 2.2, 3.6, 2.0, respectively).”

 

According to the news reporters, the research concluded: “Exposure to BDEs 47, 99, and 100 is associated with

thyroid disease in a national sample of U.S. women, with greater effects observed post-menopause, suggesting

 

 

that the disruption of thyroid signaling by PBDEs may be enhanced by the altered estrogen levels during

menopause.”

 

For more information on this research see: PBDE flame retardants, thyroid disease, and menopausal status in US

women. Environmental Health, 2016;15():1-9. Environmental Health can be contacted at: Biomed Central Ltd, 236

Grays Inn Rd, Floor 6, London WC1X 8HL, England. (BioMed Central – www.biomedcentral.com/; Environmental

Health – www.ehjournal.net)

 

Our news journalists report that additional information may be obtained by contacting J.G. Allen, Natl Canc Inst

NIEHS, Res Triangle Pk, NC, United States. Additional authors for this research include S. Gale, R.T. Zoeller, J.D.

Spengler, L. Birnbaum and E. McNeely.

 

Keywords for this news article include: Research Triangle Park, North Carolina, United States, North and Central

America, Thyroid Diseases and Conditions, Endocrine System Diseases, Flame Retardants, Thyroid Diseases,

Women’s Health, Endocrinology, Estrogens, Menopause, Hormones, Genetics, National Cancer Institute.

 

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2016, NewsRx

LLC

DETAILS

Subject: Womens health; Fire resistant materials; Health risk assessment; Estrogen

Location: United States–US

Company / organization: Name: National Cancer Institute; NAICS: 923120

Identifier / keyword: City:Research Triangle Park State:North Carolina Country:United States Region:North

and Central America Thyroid Diseases and Conditions Endocrine System Diseases

Flame Retardants Thyroid Diseases Women’s Health Endocrinology Estrogens

Menopause Hormones Genetics

Publication title: Women’s Health Weekly; Atlanta

First page: 4357

Publication year: 2016

Publication date: Jun 23, 2016

Publisher: NewsRx

Place of publication: Atlanta

Country of publication: United States, Atlanta

Publication subject: Medical Sciences, Women’s Interests

 

 

 

Database copyright  2020 ProQuest LLC. All rights reserved. Terms and Conditions Contact ProQuest

ISSN: 10787240

Source type: Wire Feeds

Language of publication: English

Document type: Expanded Reporting

ProQuest document ID: 1797342407

Document URL: https://lopes.idm.oclc.org/login?url=https://search.proquest.com/docview/1797342

407?accountid=7374

Copyright: Copyright 2016, NewsRx LLC

Last updated: 2017-11-24

Database: ProQuest Central