Homework Assignment #1 (25 marks)
Due date: Sept 16th, 2015 at 4 pm
(Use normal reference values in your notes to answer the following questions)
Q1. Use the following laboratory report for a diabetic patient to answer the questions that follow
Na+ = 136 mmol/l;
K+ = 5 mmol/l;
Cl– = 97 mmol/l;
HCO3– = 13 mmol/l
i. Calculate the anion gap ( 2 marks)
ii. Explain the significance of the value obtained in (i) above ( 5 marks)
Q2. A young woman is admitted to hospital unconscious following a fall. Her respiratory rate is persistently rapid. The laboratory report is as follows
pH 7.48, pCO2 3.9 kPa, pO2 12 kPa, SBC19 mmol/l
i) Comment on and interpret all the biochemical data (using correct biochemical terms) (5 marks).
Q3. The arterial blood gas analysis (ABG) laboratory report is as follows (10 marks)
Q4. Electrophoresis is a common technique utilized in the clinical laboratory for a wide range of applications.
i.Define the principles behind electrophoretic separation 
ii. State two different mediums used in electrophoresis 
iii. State two related electrophoretic techniques 
iv. List two stains commonly used to visualize bands of interest 
v. Name two applications of electrophoresis in the clinical laboratory 
vi. State two advantages of capillary zone electrophoresis over standard electrophoretic separation techniques 
Q5. Outline the methods available for measurement of plasma creatinine concentration.
Q6. Describe BUN (Blood Urea Nitrogen)
Q7. Discuss clinical importance of Glomerular Filtration Rate (GFR)
Q8. Describe Ketone Bodies formation.